The Clinical Trials Unit (CTU) at the London School of Hygiene & Tropical Medicine is a world renowned centre of excellence in the design, conduct, analysis and reporting of clinical trials of and is fully registered with the UK Clinical Research Collaboration (UKCRC). Additionally, we have extensive knowledge and practical experience of dissemination of results, conducting systematic reviews and research into trial methodological issues. Our team consist of expert clinical trialists, methodologists, statisticians, trial management and data management teams, trial administrators and IT systems operators. The Cochrane Eye, Heart and Injuries Groups are an integral part of our team. As our CTU is based within the largest school of public health in Europe, we have an extensive body of expertise on which we can draw, with senior academics in a range of disciplines including epidemiology, medical statistics, health economics, decision analytic modelling, and social sciences.