The show is set in the suburbs of Houston, Texas, and stars Reba McEntire as a wisecracking single mother Reba Nell Hart, whose dentist ex-husband Brock (Christopher Rich) has left her to marry young, ditzy Barbra Jean (Melissa Peterman) his dental hygienist after an affair with her, when it is revealed in the pilot episode that Barbra Jean is pregnant. Ironically, though Reba sees "B.J." (Barbra Jean's nickname) as her nemesis, Barbra Jean considers Reba her best (and perhaps only) friend. As the show progresses Reba slowly and painfully comes to the conclusion that despite all her efforts to hate her, she likes Barbra Jean and considers her a friend. In the pilot episode it was revealed that Reba's oldest daughter, then high school senior Cheyenne (JoAnna Garcia), is pregnant.
Cheyenne married her baby's father, fellow high-schooler Van Montgomery (Steve Howey), a dim-witted but well-meaning football player. Van moves in with them, as his own parents kicked him out for standing by C