The Manny Pacquiao vs. Antonio Margarito fight on November 13, 2010, was a clash of speed, skill, and heart against size, power, and reach. Billed as the "Fight for Supremacy," it took place at the Cowboys Stadium in Arlington, Texas, with the WBC Super Welterweight title on the line.

Margarito, significantly taller with a 17-pound weight advantage, aimed to use his size to overwhelm Pacquiao. His camp had even mocked Pacquiao's coach, Freddie Roach, stooping to ridicule his Parkinson's disease. But inside the ring, the tables turned.

From the opening bell, Pacquiao's speed and precision were unmatched. He darted in and out, landing powerful combinations that repeatedly found their mark. Margarito's strategy to wear Pacquiao down with body shots occasionally worked, but Pacquiao's resilience shined through.

The 11th round was a masterclass in dominance. Pacquiao unleashed a relentless barrage of punches, visibly battering Margarito. Yet, in a display of sportsmanship, he looked to the referee, signaling it was time to stop the punishment.

In the end, Pacquiao secured a unanimous decision, becoming the first boxer in history to win world titles in eight weight divisions. It wasn't just a win; it was a statement-skill, heart, and respect triumph over all.