The 100 Girlfriends Who Really, Really, Really, Really, Really Love You (Japanese: 君のことが大大大大大好きな100人の彼女, Hepburn: Kimi no koto ga Dai Dai Dai Dai Daisuki na Hyaku-nin no Kanojo), often referred to simply as The 100 Girlfriends (100人の彼女, Hyaku-nin no Kanojo), or Hyakkano (100カノ), is a Japanese manga series written by Rikito Nakamura and illustrated by Yukiko Nozawa. It has been serialized in Shueisha's seinen manga magazine Weekly Young Jump since December 2019, with its chapters collected in 17 tankōbon volumes as of March 2024. The manga has been licensed for English release in North America by Seven Seas Entertainment. An anime television series adaptation by Bibury Animation Studios was broadcast from October to December 2023. A second season has been announced.

The series focuses on high school student Rentarō Aijō, who in his lifetime fell in love and confessed to exactly 100 girls, only to be rejected by all of them. While praying in a shrine, Rentarō is approached by the God of Love, who reveals that he, due to an error, is destined to have 100 soulmates. However, he also tells Rentarō that if he does not return the feelings of any of his soulmates, they will suffer an accident and die. Not wanting this to happen, and genuinely being in love with all of the girls, Rentarō is determined not to let any of his soulmates die as he meets and dates them all at the same time.